Lymph nodes that do not disappear in three years may be malignant. The specific situation needs to be combined with the etiology and clinical symptoms to make a preliminary judgment. There are many causes of swollen lymph nodes, and it is necessary to clarify what causes are responsible for the swollen lymph nodes in order to determine whether they are malignant. If the swollen lymph nodes are caused by inflammation, usually no malignant tumor will occur. If the swollen lymph nodes are caused by tumor stem cells, they may be malignant, mostly due to the invasion of tumor stem cells, and the possibility of cancer is higher. In addition, according to their specific conditions, if the patient often has painful feeling and gradually loses weight, it may be a malignant condition; if there is no painful discomfort, it is generally benign. Therefore, lymph nodes that do not disappear in three years may be malignant, so you can consult the general surgery department for detailed examination to clarify, and if necessary, take pathological examination for further diagnosis and treatment.