Patient: I have been taking thalidomide tablets 0.1 grams per night for nearly ten days, and in the past few days, I found that my weight has increased by 6 pounds, and my face is swollen, I wonder if it is a side effect of this drug, if so, can I continue to take it? Huang Yihong, Department of Rheumatology, Shenzhen Second People’s Hospital: The adverse effects of thalidomide include: 1. gastrointestinal discomfort such as dry mouth, nausea, vomiting and abdominal pain. 2. 2, dizziness, headache, drowsiness, skin rash and facial edema. 3, can cause fetal abnormalities, pregnant women are prohibited. The facial swelling you mentioned may be related to the use of this drug, it is recommended to change the drug.