Generally, it is best to take grape seeds in the morning and evening after meals to enable the body to absorb the maximum amount of active ingredients in grape seeds. Since grape seeds contain a large amount of amino acids with rich vitamins and other nutrients, they can remove the waste in blood vessels, slow down the aging of the skin, enhance the elasticity of the skin, and also prevent atherosclerosis of blood vessels, lower cholesterol and effectively reduce blood lipids. Usually grape seeds can be taken 2 times a day, with better results after breakfast and dinner. Since grape seeds can be digested and absorbed within 4 hours after entering the body, taking them after breakfast and dinner can achieve full absorption and digestion, especially before 8:00 am, which is more beneficial to the body’s absorption. In addition, it is not recommended to take grape seeds before bedtime. Taking grape seeds before bedtime can produce a certain degree of excitement, which can affect normal sleep.