Cholecystitis and gallbladder stones are one of the common lesions in CT health checkups, and the age of onset is getting younger and younger. Most people do not eat breakfast, especially young people, work and study intensely, busy all day, and eat and drink at night. So why does not eating breakfast lead to gallbladder lesions? If you do not eat breakfast, fasting time is too long, the storage of bile in the gallbladder for too long, resulting in supersaturation of cholesterol in the bile, which in turn causes cholesterol deposition and gradually form stones. The incidence of gallstones is much higher in people who do not eat breakfast than in those who have a regular diet. Acute attacks of cholecystitis and gallstones are easily diagnosed, often in the evening or early morning after a full meal (especially greasy diet), with pain in the right upper abdomen or epigastrium, which can radiate to the right scapula and back, often accompanied by nausea and vomiting, while chronic ones are easily overlooked. Most of the cholecystitis and gallstones found on physical examination cannot say when the disease started, and it is only after detailed medical history that frequent epigastric discomfort, or vague pain, or even no symptoms are found. The most frightening thing in such chronic cases is the further development of gallbladder cancer. The gallbladder wall is irregularly thickened and fluid density shadow is seen around the gallbladder. Fluid density shadow can also be seen in the peritoneal cavity. It is already an advanced stage of gallbladder cancer.