Syphilis stage III is not curable. Stage III syphilis has serious damage to many organs, and drug treatment can only control inflammation, but the damaged organs cannot be restored, so the treatment of syphilis emphasizes early diagnosis, early treatment, a regular course of treatment, and adequate dosage. Early syphilis can be clinically cured after thorough treatment to eliminate infectiousness. Treatment is also relatively simple, and penicillin drugs are generally chosen, such as aqueous penicillin, procaine penicillin, benzathine penicillin, etc. Patients who are allergic to penicillin can also use tetracycline as well as erythromycin. Syphilis treatment is relatively simple, but it must be adhered to because the treatment takes a long time, 3 years.