With the improvement of living standards, people’s health awareness is increasing and health checkups have become quite popular. Many people find out they have gallbladder stones after checkups and feel particularly nervous, not knowing how to deal with them. Gallbladder stones are a common disease, as early as in 1987, China’s ultrasound census of healthy people 370,000 people, gallbladder stones detection rate of 1.9% ~ 9.0%, the situation in various cities are: Beijing 4.3%, Tianjin 8.2%, Shanghai 4.2%, Kunming 5.9%, the overall 6.6%. That is, nearly 7 out of 100 people who normally consider themselves healthy are found to have stones; autopsies of people who died from other causes also prove a 7% incidence of gallbladder stones. In fact, there are many people who are healthy carriers and can be asymptomatic for life. But what exactly should be done? Is it observation, surgery or conservative treatment? It is important to differentiate the treatment according to the presence or absence of symptoms, the function of the gallbladder and the age of the patient. The basic principles are as follows: 1. Without any symptoms, especially in young patients (under 35 years old) with good gallbladder function, you can follow up and observe, and review ultrasound every 3 to 6 months. 2, although asymptomatic, but the stone is greater than 2.5cm, gallbladder wall increase, sometimes combined with calcification, age greater than 50 years old, can consider preventive removal of gallbladder. 3.Symptomatic that combined with cholecystitis, usually non-specific digestive symptoms, such as indigestion, epigastric support, aversion to grease, aggravated by fatty meals or alcohol; if the stone is embedded in the neck of gallbladder or gallbladder duct, it will cause symptoms of acute cholecystitis: severe pain in the right upper abdomen, nausea, vomiting, fever and jaundice. All these cases need surgical treatment. 4. If the gallbladder is non-functional, conservative treatment is ineffective and cholecystectomy must be performed. The function of the gallbladder can be determined by ultrasound examination. If the gallbladder is functional, conservative treatment can be tried, and all kinds of litholytic and cholagogic drugs have certain efficiency, but the cure rate is low, and stone residue is more common, and even if it is completely eliminated, it is often easy to recur, and the recurrence rate is often more than 50% within 5 years. 6. Preserving the gallbladder and simply removing the stones, i.e. gallbladder incision and stone extraction, is only suitable for particularly young people, under 30 years old, with good gallbladder function and symptoms. However, after stone removal, because gallbladder stones often have an individual anatomical etiology, i.e. abnormal gallbladder development, many patients recur again after several years and end up undergoing cholecystectomy. What are the effects of cholecystectomy on the body? Most patients have a non-functioning gallbladder and have no significant discomfort after removal. In some cases, the gallbladder is still partially functional, and steatorrhea and an increased incidence of colonic lesions can occur after gallbladder removal. In conclusion, gallbladder stones should not be blindly treated by cholecystectomy, nor should they be observed without treatment, but should be analyzed according to whether the patient has symptoms and whether the gallbladder is functional or not.