Uric acid is the end product of purine metabolism and is mainly produced by the enzymatic breakdown of nucleic acids and other purine compounds from cellular metabolism as well as purines from food. Whether you can drink yogurt with high uric acid depends on whether yogurt has any effect on uric acid concentration. There are two main causes of high serum uric acid, namely increased uric acid production and decreased uric acid excretion, and sometimes both of them coexist. Increased uric acid production: mainly includes high purine dietary intake and increased endogenous purine metabolism. Food-induced uric acid production is proportional to the purine content of food, and purine-rich foods include animal liver, kidney, anchovies, etc. The increase of endogenous purine metabolism in the body is mainly related to the synthesis and decomposition of purine. Decreased uric acid excretion: About 2/3 of uric acid is excreted through the kidneys, and the remaining 1/3 is excreted through extrarenal pathways such as the intestinal tract and biliary tract. About 90% of patients with persistent hyperuricemia have a defect in renal processing of uric acid and show reduced uric acid excretion, including reduced glomerular filtration rate, increased tubular reabsorption, reduced tubular secretion and urate crystallization. Patients with hyperuricemia should strictly adhere to the dietary principle of low purine diet. All foods with low purine content can be consumed, such as most vegetables, fruits, dairy products, rice and noodles, which are low in purine content and suitable for daily consumption. In general, yogurt is not rich in purines, so patients with high uric acid can drink yogurt appropriately. Therefore, patients with high uric acid should strictly adhere to the dietary principle of low purine diet, but yogurt is not rich in purines, so it is possible to drink it.