Scleroderma can be divided into two types: limited scleroderma and systemic scleroderma, with different types and different treatments. 1. Limited scleroderma: early patients can use topical glucocorticoid or intradermal injection of glucocorticoid. Limited scleroderma is also divided into block scleroderma and linear scleroderma two types, linear scleroderma, especially across the joints should pay attention to joint activities, with a variety of physical therapy to prevent joint contracture, activity limitation. 2. Systemic scleroderma: nifedipine, tolazoline, prostaglandin E1 can be used to treat vasospasm; anti-sclerosis treatment can be used D-penicillamine, colchicine and so on; Glucocorticosteroids can only be used for patients with rapid progression of the disease; methotrexate, cyclophosphamide also has a certain effect on the skin lesions; finger ulcers should be cleared and topical antibiotics and vasodilator ointment, accompanied by painful calcified nodules can be surgically removed. The above drugs should be taken under the guidance of a doctor. When scleroderma is diagnosed, it is recommended to consult a doctor in time and standardize the treatment under the guidance of a doctor.