Mr. Chen, 59, started to experience symptoms of droopy eyelids, general weakness and shortness of breath 3 months ago. After going to the hospital for examination, he was diagnosed with eruptive myasthenia gravis. Surprisingly, he also suffered from thymoma and early lung cancer at the same time, one person suffering from three serious diseases at the same time! Recently, the thoracic surgery department performed thymoma and thymus enlargement resection and complete lung cancer resection for the patient through only one operation and one incision, and the operation went very well. After the operation, under the combined treatment of ICU and neurology, the patient resumed autonomous breathing and was discharged from the hospital. Mr. Chen, who is nearly an old man, is an outdoor sports enthusiast and often climbs mountains with his partner on rest days. Unexpectedly 3 months ago suddenly found both sides of the eyelids have signs of sagging, and the symptoms are light and heavy at night. Chen Sheng began to think it was not well rested, but did not want the condition to progress rapidly, and soon there was general weakness, walking a few steps to panting. The previous climb to the top of Baiyun Mountain did not feel tired, but now walk a hundred or eighty meters to sit down to rest, more uncomfortable is that eating are weak swallowing. The family was very nervous and rushed to the hospital for medical attention. The family was shocked when the test results came out: Chen Sheng not only suffered from violent myasthenia gravis, but also found a 6cm-long tumor on the thymus, the size of a plum, and more frighteningly, a mass in the lower right lung, which was diagnosed as lung cancer! The doctor could not help but exclaim, “It’s really rare!” that these three diseases were found in one person at the same time. When he was admitted to the hospital, Chen Sheng had breathing difficulties and needed tracheal intubation and ventilator-assisted ventilation. The family looked at Mr. Chen, who was unable to breathe on his own and whose life was worse than death, and was very anxious. One surgery with one incision cleverly treated 3 diseases In response to the patient’s condition, the thoracic surgery department had repeated discussions with the neurology department and ICU. Due to the large size of the thymoma tumor, it was agreed that the only option was open-heart surgery, and that the thymoma and enlarged thymectomy and complete right lower lung cancer resection would be performed simultaneously in one surgery. Although the enlarged thymus and complete resection of thymoma could be ensured intraoperatively, the complete resection of right lower lung cancer posed a great challenge due to the obstruction of the heart and the difficult anatomy of the hilar structures. Therefore, the operation is very difficult and risky, and requires a high level of skill and very delicate operation to ensure the success of the operation. After thorough preoperative preparation, Chen Gang, the chief surgeon, performed a median open thoracotomy, enlarged thymectomy, right lower lung lobectomy and mediastinal lymph node dissection, enlarged thymus and complete resection of right lower lung cancer and thymoma, which took 5 hours and was a complete success! After the operation, with the cooperation of ICU and neurology, Mr. Chen quickly resumed his autonomous breathing and was discharged from the hospital. Surgery is the best treatment for myasthenia gravis Myasthenia gravis is an autoimmune disease that is closely related to the thymus gland. Drug treatment can only relieve the symptoms and cannot completely stop the progression of the disease, and surgery is the most likely treatment to cure myasthenia gravis. For patients without combined thymoma or with smaller thymoma, minimally invasive thoracoscopic surgery can be performed without opening the sternum, resulting in less trauma and better results.