Aminotransferase is an enzyme protein present in liver cells or bile duct cells and is one of the important indicators of liver function tests. A high transaminase of 100 U/L is usually not very serious if other test indicators are normal. However, if it is accompanied by other test indicators abnormal, or accompanied by jaundice, abdominal pain and other symptoms, it may be more serious, especially in patients with compensated cirrhosis, where the transaminase is not very high but the condition is more serious. Aminotransferase is an enzyme that exists mainly in liver cells. When 1% of liver cells in the body are damaged, inflamed or necrotic, it can cause aminotransferase to enter the blood from the liver cells, thus causing an increase in serum aminotransferase. The normal value of aminotransferase is usually 40 U/L. When the aminotransferase increase is less than 3 times the normal value, it is mildly elevated, and when it is 5-10 times the normal value, it is significantly elevated. Therefore, a transaminase of 100 U/L indicates damage to liver cells, which is considered mild. If the aminotransferase is elevated to 100U/L, if other indicators are normal, it is usually not very serious and may be alcoholic liver, fatty liver and drug-related liver damage, etc. Most patients can recover on their own by promptly quitting alcohol, eating a light diet and stopping the use of liver damage drugs. If it is viral hepatitis, which has not yet developed to the stage of cirrhosis, it is usually not very serious and can be controlled by oral antiviral drugs or interferon injections. If it is already in the compensated stage of cirrhosis, this is a more serious situation and requires timely treatment to avoid progression to the decompensated stage.