Seven years ago, a patient from Henan Province was brought to our Anzhen Hospital by emergency. He was diagnosed with coronary heart disease at the local county hospital, but each attack was different from the usual coronary heart disease. Every time he had an attack, he would have panic attacks, chest pain, a sense of near death, and an abnormal feeling of pain, which could not be controlled by almost all medications. (Most episodes of coronary heart disease can be relieved by appropriate medication or treatment.) Many drugs were used in the local hospital, but all of them could not be controlled. After several cycles of treatment, the patient was almost desperate. When he came to our hospital, he said to me, “Dr. Liu, if you can’t save me anymore, I will have no way out, I even think about my afterlife.” In addition, the patient’s mood was so bad that he was almost going crazy. After our screening, we found that he was a typical psychological heart patient. He himself did have coronary heart disease and there was no error in the treatment by the local doctors, but the treatment of psychological neuromodulation was neglected. This patient’s mother died shortly after, and he was very stressed psychologically, with significant anxiety. His psycho-emotional problems activated the sympathetic nervous system in his body, causing the small blood vessels of the heart to constrict, thus producing the associated symptoms. In his specific case, we treated his coronary artery disease while improving his psychological and neurological regulation problems. After a week of treatment, the number of episodes in this patient dropped from dozens a day to a few times a day. After that, the number of attacks decreased again to once every few days. After that, he never had any more seizures. Until now, this patient is doing very well. How does psychological heart disease relate to what the people often call heart disease? Does it exist independently, or does it occur at the same time as heart disease? In clinical practice, we call panic attacks and chest tightness non-specific symptoms, sometimes accompanied by dizziness, headache, weakness and lack of desire to eat. If these problems occur persistently, or if they occur in one episode but the symptoms are very pronounced, the first thing to consider is the presence of organic heart disease. If none of the relevant tests are problematic, that is, if the patient’s subjective symptoms do not quite match the objective findings, we consider whether the patient has functional heart disease, such as certain heart problems caused by psycho-emotional issues. In the past, we diagnosed this condition as cardiac neuropathy because it was mainly related to neuromodulation. However, as research has progressed, cardiac neurosis no longer encompasses all of the categories of functional heart disease. As a result, the condition is now referred to as psychological heart disease, or bipolar heart disease.