Ankylosing spondylitis has a long history of understanding in Chinese medicine, with the Yellow Emperor’s Classic of Internal Medicine discussing “bone paralysis” and “kidney paralysis,” and ankylosing spondylitis can be classified as “paralysis” in Chinese medicine. According to Chinese medicine, “wind, cold, and dampness are combined to cause paralysis”, which is the external cause of paralysis. The key to the pathogenesis of paralysis is the congenital deficiency of kidney essence and the emptiness of the Governor’s Vessel, while the evil of wind, cold, dampness and heat is the precipitating factor and is related to the internal obstruction of blood stasis and the blockage of the Governor’s Vessel. According to clinical epidemiological studies, modern ankylosing spondylitis is dominated by three types of evidence: damp-heat paralysis, kidney yang deficiency, and blood stasis paralysis, and damp-heat paralysis and kidney yang deficiency are the main evidence, while blood stasis paralysis is mostly a part-time evidence. Therefore, tonifying the kidney and invigorating the blood, clearing heat and dampness and invigorating the blood are the main treatment rules for ankylosing spondylitis in Chinese medicine, supplemented by expelling wind, dispersing cold, resolving phlegm and clearing the ligaments. The main treatment for ankylosing spondylitis is to expel wind, disperse cold, and remove phlegm. In short, according to the Chinese medical diagnosis and treatment, supplemented by acupuncture, Chinese medicine fumigation is currently the main method of Chinese medicine treatment of ankylosing spondylitis, and in the clinic to achieve better results, is a useful choice for patients with ankylosing spondylitis.