Ankylosing spondylitis is a chronic, progressive inflammatory disease that primarily affects the sacroiliac joints, spinal eminences, paraspinal soft tissues, peripheral joints, and areas where tendons and ligaments attach to bone. The disease has a tendency to accumulate in families, and patients are mostly positive for HLA-B27 (a locus on the human leukocyte antigen). Professor Zhang Nai Zheng and other investigations, the prevalence of ankylosing spondylitis in China is about 0.26%, the age of onset is common in 20-30 years, the ratio of men to women is 2-3:1. Ankylosing spondylitis can not be cured, but with age, some patients are self-limited and the disease gradually stabilizes. Some patients may be prolonged. The disease is highly variable among individuals, and patients with mild disease may not require medication and their functional status and ability to work are not affected. In severe cases, failure to treat the disease systematically may result in hunchback and joint deformities. If the diagnosis of ankylosing spondylitis is made, the first thing to look at in conjunction with their own symptoms, whether there is a feeling of stiffness in the back when waking up in the morning, whether there is swelling and pain in the joints, whether there is fatigue in general, check the blood sedimentation, c-reactive protein is not significantly elevated, if all these indicators are present, that suggests a high degree of disease activity, the need for active treatment, the future existence of spinal deformation, hunchback may. The goal of treatment for ankylosing spondylitis is to alleviate symptoms, control disease progression and prevent deformity. Exercise is as important as medication in the recovery process of ankylosing spondylitis!!! Uninterrupted and reasonable physical exercise is required during the day. Such as deep breathing, swimming, neck and lumbar activities to maintain the physiological curvature of the spine. Do more chest expansion exercises to increase lung capacity. Sleep on a hard bed, use a short pillow, sit on a high wooden chair, sit less on a sofa, stand up straight with your stomach up, sleep on your back and less on your side. The department has a chart of functional exercises for patients with ankylosing spondylitis, so please feel free to ask for it. If the economy allows, tumor necrosis factor receptor antibody fusion protein is often very effective for this disease. If the economic situation is average, slow-acting anti-rheumatic drugs can be used as appropriate, as they have a stabilizing effect on the disease.