Hepatitis B is one of the manifestations of the interaction between the hepatitis B virus and the host, and vaccination of uninfected individuals is a very effective preventive measure. 2, hepatitis B virus infection has a series of disease spectrum with its own characteristics, namely carrier status, hepatitis B, cirrhosis, liver cancer, different infected people and different stages of the same infected people have different forms of expression. 3.HBV infection will accompany the host for a long time and requires long-term treatment. 4.At present, effective reduction of viral load is an effective and important means to reduce the disease and slow down the progress. The viral load can be rapidly reduced by rationalizing the use of drugs, but there are no effective drugs to clear the virus. Different patients respond differently to different antiviral treatments, and individualized treatment is emphasized. Try to choose drugs that are potent, low resistance and have few side effects. 5. The goal of treatment is to effectively stop or delay disease deterioration and progression in order to improve quality of life and extend life expectancy.