Anti-streptococcal hemolysin O high in the body has a lot of harm, anti-streptococcal hemolysin O in the body is a specific indicator for the diagnosis of group A streptococcus, the body continues to increase anti-O will cause serious rheumatic fever, such as rheumatoid arthritis, rheumatoid arthritis will appear when anti-O increased situation. An increase in globulin O also indicates that the body may be suffering from acute glomerulonephritis, acute crescentic nephritis or acute nephrotic syndrome, when there is also a persistent increase in anti-streptolysin O in the body. In addition, connective tissue diseases, such as systemic lupus erythematosus, may also have increased anti-streptococcal hemolysin O. In the case of viral myocarditis, there is also a persistent increase in anti-streptococcal hemolysin O. Therefore, increased anti-O is harmful to the body and must be treated in a timely manner.