Current treatment for ankylosing spondylitis consists of anti-inflammatory and biologic agents (Ixepro, Enzyme, Classic, Xumel, etc.) These methods aim to control disease activity, but are often prone to relapse after discontinuation of the drug. With the use of periodic killing (in addition to the original treatment regimen), patients were found to have easier control of disease activity and could maintain disease remission for a longer period of time. With periodic killing therapy, the majority of patients have effective control of their disease, and some have been off the medication for as long as 3-4 years. The rationale for regular toxicity control is that infection is a trigger for ankylosing spondylitis disease activity, but infection is unpredictable and some germs that do not cause any symptoms in the body can trigger ankylosing spondylitis disease activity. Regular antivirus is the regular removal of bacteria and viruses from the body to prevent these viral bacteria from inducing disease activity. Just like we regularly kill the virus on our computers. Preliminary studies have found that regular killing reduces the use of drugs and biological agents. For patients whose illnesses are difficult to control, try regular killing. For those patients who are prone to colds, it may be necessary to boost the immune system to achieve better results.