There is a high percentage of hepatitis B virus infection in our general population, so there are many people infected with hepatitis B virus among uremic patients. Uremic patients are mostly treated with hemodialysis for a period of time, during which most patients have received blood or blood products because of anemia, etc., so they have more chances of hepatitis B virus infection than the general population, so will the results of these people be better if they receive kidney transplantation than Hemodialysis? There is still great controversy, but there is evidence that the immunosuppressed state after kidney transplantation activates the virus, accelerates its replication and aggravates the progression of liver disease. However, the prognosis is better if HBsAg-positive recipients are free of viral replication at the time of kidney transplantation.