Sternal pressure pain is a common sign of leukemia, which can be treated with pain-relieving drugs such as morphine, and active radiotherapy and chemotherapy for leukemia itself to reduce the symptoms of sternal pressure pain. 1. A large number of leukemia cells proliferate in the bone marrow of leukemia patients, leading to increased pressure in the marrow cavity, leukemia cells infiltrate the periosteum, stimulate the sensory nerves, and produce severe pain, which often occurs in the middle and lower part of the sternum. In this case, you can take some pain relieving drugs under the guidance of doctor, such as ibuprofen, morphine, tramadol and so on. 2. In addition, the sternal pressure pain itself is caused by leukemia, so it is also necessary to carry out systematic treatment of leukemia, the clinical usually take the method of radiotherapy, the drugs include cytarabine, Zoerythromycin and so on. As long as the leukemia is well controlled, the sternal pressure pain will also be relieved to a certain extent. Once leukemia is diagnosed, it is necessary to standardize the treatment as early as possible under the guidance of physicians to effectively control leukemia and prolong the survival period.