Although surgical resection is the first choice in liver cancer treatment, the key to achieve satisfactory results is early diagnosis. Historically, early detection of liver cancer is difficult, and once detected, it is mostly in the middle or late stage. According to the statistics, the surgical resection rate is 5%-25%, and the survival rate is only 30% in 1 year after surgery, and the quality of survival is poor. Interventional therapy mainly based on hepatic artery chemoembolization has achieved definite efficacy and is considered as the preferred method among non-surgical treatments for hepatocellular carcinoma, and has become an effective measure before second-stage surgery mainly in the following two ways intra-arterial infusion of chemotherapeutic agents. This can increase the local drug concentration in the target cells and prolong the contact time between the drug and the lesion, and reduce the total dose of the drug throughout the body to achieve the purpose of improving the efficacy and reducing the side effects. The efficacy of chemotherapeutic drugs is positively correlated with the effective blood concentration of drugs at the tumor site and the contact time of drugs with the tumor. The blood supply of normal hepatocytes is 20%-50% from the hepatic artery and 75%-85% from the portal vein. In primary tumors, 90-95% of the blood supply comes from the hepatic artery, which provides an anatomical basis for selective transhepatic arterial perfusion for tumor treatment. There are three types of clinical perfusion methods: (1) One-shot: It refers to the method of injecting drugs into the target artery in a short period of time and then withdrawing the tube to end the treatment. It is characterized by rapid operation, few complications, simple care, and is suitable for sites where catheter retention is difficult. (2) Arterial block chemotherapy: It is a method of inserting a blocking balloon catheter into the target artery, then causing the balloon to expand to block the arterial blood flow, and then infusing chemotherapy drugs. The purpose is to further increase the drug concentration and prolong the drug arrest time. (3) Long-term drug perfusion: This method has a longer catheter retention time, and perfusion can be continuous for several times. (2) Hepatic artery embolization therapy A certain solid or liquid substance is selectively injected into tumor blood vessels and tumor blood supply arteries through catheter to block tumor blood supply and inhibit tumor growth. For tumors that cannot be removed surgically, this therapy can shrink the tumor and reduce the pain and other complications to achieve the purpose of delaying life and improving the quality of survival. Types of embolic agents: (1) Long-term embolic agents. Gelatin sponge: It is a non-toxic, non-antigenic protein gelatinous substance, which is one of the commonly used embolic agents. Iodine oil: It disappears in normal tissues after a few days after being injected via arteries, and stays in tumor tissues for a long time, which can be several months or more than one year. Iodine oil can also be made into emulsion or suspension with anti-cancer drugs as a carrier of anti-cancer drugs, so that the drugs can stay in the tumor for a long time at a high concentration and be released slowly to increase the anti-cancer effect of the drugs. (2) Chinese medicine embolic agent. The embolic effect may be achieved by activating the coagulation system and causing extensive thrombosis in the arteries. Cajeput oil has both anticancer and arterial embolism effects. Curcuma longa oil: In addition to being an embolic agent, curcuma longa oil has obvious anti-cancer effects, inhibiting the synthesis of nucleic acid in cancer cells and causing the death of cancer cells. It also has the effect of enhancing the immune function of the body. It has been reported that the 1, 2 and 3-year survival rates of liver cancer treated with interventional methods are 44%, 29% and 15% respectively, which are significantly better than other treatment methods. At present, interventional therapy is increasingly used in tumor treatment and can be used for many solid tumors such as lung cancer, ovarian cancer, cervical cancer and pancreatic cancer.