Clinically, inactive or mostly inactive spermatozoa are defined as necrozoospermia. In fact, dead spermatozoa are certainly immobile, but immobile spermatozoa may not always be dead, only through the eosin or TP staining survival rate of less than 50% can make the diagnosis of necrospermia. The cause of azoospermia is complex, but it is generally believed to be related to inflammation of the accessory sex glands and epididymis. Special attention should be paid to the inflammation of the epididymis and pathological changes in the epididymis. The treatment of azoospermia is very difficult. The most important thing is to remove the cause of the disease. Such as anti-inflammatory treatment and remove the effect of toxic substances on spermatozoa, can also be carried out in vitro treatment of spermatozoa vivisection, so that the survival but inactive spermatozoa swimming, and on this basis, the active spermatozoa separation, through artificial insemination can be or in vitro fertilization fertilization to help fertilization.