Patients with depression can have early awakening, but early awakening can also be caused by other diseases, such as neurasthenia, difficulty falling asleep or having more dreams during sleep, and some patients can also have weakness of limbs, palpitations, chest tightness, shortness of breath and so on. The disease can occur at any age and may be caused by prolonged mental tension, stress or irregularity in life, excessive late nights, and is mainly regulated by taking oral glutamatergic tranquilizer. In case of depression, patients may also have psychological symptoms, mainly manifesting as reduced self-evaluation, loss of confidence in life, disinterest in anything, reluctance to communicate with others, and communication with others; they may also wake up early during sleep, and generally do not have difficulty falling asleep; they may also have more dreams during sleep, and mainly take oral citalop for conditioning.