Do you know about artificial insemination? Artificial insemination is the insertion of sperm into the woman’s reproductive tract through non-coital means. It is divided into intrauterine and intravaginal insemination; and according to the source of sperm, it is divided into husband sperm insemination and donor sperm insemination. Donor sperm requires sperm from a sperm bank. The Guangzhou General Hospital of Guangzhou Military Region Reproductive Medicine Center Ge Mingxiao Who is suitable for artificial insemination? 1, Semen cannot enter the female reproductive tract normally: such as impotence, premature ejaculation, non-ejaculation. 2, Abnormal semen: oligosperm, weak semen, semen not liquefied or long liquefaction time, severe low semen volume, so that semen cannot touch the cervical opening. 3. Immune infertility of both sexes 4. Unexplained infertility: the female partner has ovulation, the fallopian tubes are open, the male partner’s semen is normal, and both parties are negative for anti-sperm antibodies Timing of artificial insemination: Artificial insemination method: mainly introducing intrauterine insemination of the husband’s semen: before and after the female partner ovulates, her husband takes out the semen, waits for its liquefaction or assisted liquefaction, washes and centrifuges it several times, and injects 0.3-0.5ml of concentrated semen into the uterine cavity through the catheter. A catheter is used to inject the concentrated semen into the uterine cavity. Pregnancy rate of IUI: The factors affecting the pregnancy rate are the age of both partners, the cause of the disease, the number of years of infertility, the quality of the sperm, and the condition of the pelvis (the possibility of adhesions). The general pregnancy rate for a single IUI is 15-20%. The pregnancy rate for normal couples is only about 20% per ovulation cycle. However, artificial insemination is non-invasive, inexpensive and reproducible. We recommend that couples who are suitable for artificial insemination can repeat it 3-4 times, and if they are still infertile, they can do IVF instead. Artificial insemination treatment process 1, the initial consultation (with the couple’s previous medical records and all the checklists); 2, determine the artificial insemination treatment; 3, prepare the marriage certificate, birth control certificate, ID card; 4, both sides of the laboratory examination (the female fasting); 5, with the marriage certificate, birth control certificate, ID card, both sides of the laboratory checklist to establish a medical record file; 6, monitoring ovulation, check the endometrium (or ovulation promotion); 7, follicles large enough when HCG injection; 8. Sperm retrieval immediately after ovulation or 24 hours after HCG injection, artificial insemination; 9. 30-60 minutes of sedation; 10. Luteal support (application of various preparations of progesterone or HCG); 11. Pregnancy test 14 days after insemination. If pregnant, continue luteal support for 14-16 days and then ultrasound to check pregnancy. Steps and Precautions: 1) During the cycle, the woman will go to the hospital on the 10th day of the menstrual cycle to monitor the follicle development by negative ultrasound. You may be advised to abandon the cycle and wait for the next cycle or several months of medication before undergoing IUI. 3) If you have had 3-4 unsuccessful IUIs with an ovulation treatment regimen, it is not suitable for you and you should be treated with another regimen or laparoscopy or hysteroscopy to determine the next step in treatment. 4) Patients undergoing IUI must have at least one patent fallopian tube with normal egg collection, peristalsis (no pelvic adhesions) and secretion.