Patients with moderate and severe depression need to be hospitalized. Patients with moderate and severe depression are often accompanied by self-injurious and suicidal thoughts and behaviors, as well as patients have a relatively high risk of threatening their own bodies, so systematic and standardized inpatient treatment is recommended. In the process of inpatient treatment, medication, psychotherapy and physical therapy can be given to maximize the systematic, standardized, adequate and full course of treatment. The treatment effect is also very good with some antidepressants. Therefore, patients with mild depression can choose not to be hospitalized, but for patients with moderate or severe depression, hospitalization is highly recommended.