Severe depression can be accompanied by many physical symptoms and the physical symptoms can be colorful, the main manifestations are physical discomfort, pain, fatigue, autonomic dysfunction and various desires, such as loss of libido, loss of appetite, and weight loss caused by loss of appetite, the more obvious is gastrointestinal dysfunction. More serious physical symptoms are the following: 1. pain sensation, depressed patients often have unexplained pain in various parts of the body, such as headache, back pain, abdominal pain, muscle aches, etc. 2. sleep disorders, severe sleep disorders such as insomnia, early awakening, nightmares, short total sleep time, and some people will sleep too much. 3. decreased sexual desire or lack of pleasure, such as obvious loss of sexual desire The symptoms of depression may be accompanied by physical symptoms, and many male patients may have similar symptoms, and may even go to other departments for abnormal libido. 4. gastrointestinal disorders, such as nausea, vomiting, constipation, abdominal distension, and also appetite disorders, such as anorexia or bulimia, will be accompanied by significant changes in weight, such as anorexia 5. Not particularly specific physical symptoms, such as autonomic dysfunction, common cardiovascular problems, neurological symptoms, such as panic attacks, increased blood pressure or dizziness, numbness and discomfort. If the above serious somatic symptoms have appeared, it is best to actively intervene and treat them.