Carbon monoxide, commonly known as gas, is a colorless, odorless, tasteless and non-irritating gas. It can be produced by incomplete combustion of any charcoal-containing substance. When the inhaled carbon monoxide combines with hemoglobin to form stable carboxyhemoglobin, the Hb loses its oxygen-carrying capacity, thus causing the lack of vital organs and tissues, and the symptoms of central nervous system, circulatory system and other poisoning. [Clinical manifestations] 1. Mild: headache, dizziness, tinnitus, nausea, vomiting, palpitations, weakness of limbs or transient syncope. After leaving the poisoned environment and inhaling fresh air, the symptoms can disappear quickly. 2. Moderate: In addition to the aggravation of the above symptoms, a shallow coma appears. The patient’s face is flushed, lips and skin are cherry red, and the pulse is fast and sweaty and irritable, at this time, if resuscitation is timely, the patient can be awakened. 3.Severe: In addition to the above symptoms, pulmonary edema, cerebral edema, respiratory distress, cardiac arrhythmia, etc. are often complicated. If the respiratory center is paralyzed, death can occur within a short time. [Diagnosis] 1. History of CO inhalation. 2.Clinical manifestations. 3, laboratory tests: qualitative positive ODHb in blood or quantitative more than 10% can confirm the diagnosis. 4. Attention should be paid to differentiate from acute sleeping drug poisoning. [Treatment] 1. Resuscitation: leave the toxic site as soon as possible, transfer to fresh air, untie the collar and trouser belt, remove the secretions from the mouth and nose, and keep the breathing open. Give artificial respiration or tracheal intubation to those with respiratory and cardiac arrest, and inject respiratory stimulants. And pay attention to heat preservation. 2.Oxygen supply: Hyperbaric oxygen is the most effective. But the effect of poisoning more than 36 hours is very little. If there is no hyperbaric oxygen equipment, oxygen should be given by mask with oxygen concentration > 60% or by nasal catheter. 3, prevention and control of cerebral edema: apply hypertonic dehydrating agent such as 20% mannitol 250ml, and repeat 1-2 times in 8-12 hours, while alternating with tachypnea and dexamethasone 10-30mg in several injections. 4, blood transfusion or blood exchange: can rapidly increase oxygenated hemoglobin, improve tissue hypoxia, for patients in severe coma, under the premise of blood pressure stability, can release 300-400ml of blood, in strict aseptic operation conditions after oxygenation to wait for blood is bright red after input. If the above conditions are not available or the blood pressure is not suitable for bloodletting. Fresh whole blood 200-400ml can be input. 5.Improve cerebral circulation: 500ml/day of low molecular dextrose drip, 5-7 days of treatment or 500ml of 0,1% procaine, intravenous drip, finished within 2-4 hours, once a day, 5-7 days of treatment. 6.Improve brain tissue metabolism: cytochrome C 30-60mg/day intravenous drip (pay attention to skin test), brain activator 10-20ml in 250ml of saline static drip once a day, 7-10 days for a course of treatment. Cytophosphorylcholine 400-600mg once a day, and high-dose vitamin C and B. 7, artificial hibernation: suitable for patients with high fever, convulsions, can increase the brain’s tolerance to oxygen, 8, to prevent secondary infection: strengthen oral and systemic care, to prevent the occurrence of bedsores. Infections occur in a timely manner to give sensitive antibiotics. 9, acupuncture therapy: good effect on general symptoms of poisoning, place the patient in fresh air, acupuncture Hegu, Sun, Lily, Shaoshang, Yongquan as the main points, with the head dimension, Chengjue, dumb door, Fengfu, Zhongchong, Taichong, Quchi, Foot Sanli and other supporting points, each time acupuncture 2-5 points or more. Depending on the condition, the stimulation technique is selected and the needles are retained for 20-40 minutes, with twisting every 3-5 minutes.