Gastrin 17 is a gastrointestinal hormone, which mainly promotes the secretion of digestive juices and peristalsis in the gastrointestinal tract. High gastrin 17 in clinical examination generally indicates low gastric acid secretion, which may be caused by a variety of gastric diseases and needs to be combined with other examinations to determine the specific cause and choose the appropriate treatment according to the cause. Common causes: High gastrin 17 is commonly associated with chronic gastritis or gastric cancer, which can be determined by breath test to determine whether there is H. pylori infection, as well as by gastroscopy or abdominal CT to determine whether there is a possibility of chronic gastritis and gastric tumor, and if necessary, biopsy and methotrexate test are needed to clarify whether there is cancer in the stomach. In rare cases, high gastrin 17 is also associated with other digestive diseases such as intestinal polyps and duodenal ulcers. If it is clear that the high index is not caused by stomach diseases, then colonoscopy can be performed to clarify whether there are related intestinal diseases. Treatment: If it is caused by Helicobacter pylori infection, chronic gastritis, duodenal ulcer, etc., you can choose antibiotics to control the infection, such as amoxicillin, metronidazole, etc., under the guidance of a doctor, and use acid-suppressing drugs and mucosa-protecting drugs, such as omeprazole, rabeprazole, bismuth potassium citrate, etc. If it is caused by intestinal polyps, it can be treated by endoscopic surgical excision, which can obtain a better prognosis. If necessary, biopsy can be added to determine whether there is a possibility of cancer. If it is caused by gastric cancer, the main treatment is surgery, and radiotherapy, chemotherapy or targeted therapy will be performed after the lesion is removed. Note: In daily life, we should pay attention to eat less greasy food, less or no spicy, cold, sweet and greasy food, it is recommended to choose light and easy to digest food, regular and quantitative meals and avoid overeating.