Since Reich et al. performed the world’s first laparoscopic hepatectomy in 1991, the application of laparoscopic techniques in liver diseases has been gradually recognized and promoted with the continuous maturation of laparoscopic techniques. The scope of laparoscopic hepatectomy has been expanded from local resection of liver margins and superficial lesions to regular resection of half of the liver and even larger areas. Clinical studies have shown that with the increasing proficiency of laparoscopic techniques and the shortening of the learning curve, the incidence of intraoperative and postoperative complications in laparoscopic liver resection is no longer significantly different from that of open surgery and is characterized by less trauma, faster postoperative recovery, and less impact on the patient’s immune function. Its feasibility and safety in operation technology have been gradually confirmed. 1.Surgical methods: ①Total laparoscopic hepatectomy: complete liver resection through laparoscopy, small incision is only used to remove the specimen. ②Hand-assisted laparoscopic liver resection: During laparoscopic surgery, the hand is inserted into the abdominal cavity through a small incision in the abdominal wall to assist in the operation to complete the liver resection. ③Laparoscopic-assisted hepatectomy: partial operation is completed through laparoscopy or hand-assisted laparoscopy, and finally liver resection is completed through a small incision. 2.The anatomical scope of laparoscopic hepatectomy: ①Local resection is applicable to lesions located in segments II, III, IVb, V and VI. ②Anatomical resection is applicable to left hepatic outer lobe, left hemihepatic and right hemihepatic resection. Laparoscopic left and right hemihepatectomy has been proven to be feasible, but the procedure is difficult and should be performed by an experienced surgeon and surgical team. (iii) Laparoscopic resection for lesions located in segments I, IVa, VII and VIII and laparoscopic left and right trilobar resection have not been widely accepted. It belongs to the applicable scope of clinical exploratory study. 3. Indications for laparoscopic hepatectomy: (1) benign hepatic lesions: intrahepatic bile duct stones, symptomatic hemangiomas, symptomatic focal nodular hyperplasia, adenomas, multiple hepatic cysts, lesions confined to the hemihepatic; (2) malignant hepatic tumors: including primary hepatocellular carcinoma, metastatic hepatic tumors and other malignant lesions. To ensure adequate margins, it is recommended for lesions with no major ductal invasion and <3 cm in diameter. If the tumor protrudes extrahepatically and the margins can be ensured lumpectively, the tumor diameter can be extended to 5 cm; (3) For living donor liver resection for liver transplantation, including left outer lobe, left hemiportal, and right hemiportal donor livers. It has not been reported in China and is the applicable scope of clinical exploratory study; ④ Uncertain lesions of malignancy cannot be excluded. 4. Contraindications to laparoscopic hepatectomy: any contraindication to open liver resection; patients with difficulty tolerating pneumoperitoneum; dense intra-abdominal adhesions; lesions too close to large vessels; lesions too large to safely perform laparoscopic operation because they affect the exposure and separation of the first and second hilum; portal invasion and portal vein cancer thrombosis.