The most common cause of premenstrual headache is a series of symptoms that occur due to relatively obvious changes in hormone levels in the female body, as follows: 1, large amounts of prostaglandin release: changes in estrogen and progesterone levels can cause the release of large amounts of prostaglandin in the blood, prostaglandin can cause smooth muscle contraction and spasm, including uterine contraction, muscle tissue, smooth muscle tissue contraction, and also can cause smooth muscle expansion Vascular, the physiological state of vascular function is disturbed, intracranial vasospasm occurs, causing local blood supply deficiency and ischemia, in addition to this, it can also lead to muscle spasmodic contraction and cause headache; 2. Intercellular water and sodium retention: abnormally high estrogen and progesterone levels in premenstrual period, steroid hormones can lead to intercellular water and sodium retention, causing mild intracranial edema and increasing intracranial pressure, increased cranial pressure can cause headache, mood change Increased cranial pressure can cause headaches, mood changes, sleep disturbances, and thus reflexively cause changes in the hormonal endocrine environment, which can also lead to increased headaches. Premenstrual headache is usually a physiological condition, mainly caused by changes in the endocrine environment, and usually relieves quickly after the onset of menstruation. In order to alleviate the uncomfortable state, it is important to take rest, avoid staying up late, relax and improve sleep before and during menstruation, and if necessary, use antipyretic and analgesic drugs or sedative-hypnotic drugs to relieve the symptoms.