Suggestions: 1) To clarify the diagnosis, including imaging of colon and small intestine preferably endoscopy; 2) Blood picture, C-reactive protein, blood sedimentation, biochemical indexes to exclude chronic infections (hepatitis virus, tuberculosis, etc.) and lymphoma; 3) Antibiotic combination therapy for 7-10 days, then on targeted therapeutic measures; The general treatment is: first-line 5-aminosalicylic acid or its precursors; second-line glucocorticoids or immune inhibitors, 3rd line biologics. Overall, individualized and deadline-specific. It is important not to treat indiscriminately.