Patients with chronic kidney disease (CKD) are difficult to detect early due to a lack of awareness and the fact that many people are not in the habit of having regular comprehensive checkups. They often go through a long asymptomatic phase before they develop obvious clinical symptoms. It is worth noting that many “telltale signs” of chronic kidney disease can also appear in the early stage of the disease, such as: back pain, swelling, hypertension, anemia and so on. But these early symptoms are often overlooked, for example, some people think that “long-term back pain is due to sitting for a long time” and “swelling is due to not sleeping well”. In fact, these are already the alarm of kidney damage, if you continue to take the attitude of ignoring, delaying, avoiding and not seeking medical attention, it can cause irreversible results. Here is a summary of some early signs of chronic kidney disease (CKD): ` 1, morning eyelid or facial edema, after noon more subside. It usually worsens after exertion and decreases after rest. Severe edema may appear in the low hanging parts of the body, such as the inner part of both ankles, both lower limbs, and the lumbosacral region. 2.More foamy urine, which does not disappear for a long time, often indicates that more protein is excreted in the urine because of kidney damage. 3, when the urine color is thick tea, wash water-like, soy sauce color or cloudy like rice water, you should immediately consult a doctor to clarify the cause. 4.Some patients with chronic kidney disease have high blood pressure and may show symptoms such as headache, dizziness and blurred vision, but others with chronic kidney disease have tolerated it due to high blood pressure for a long time and may not show any discomfort. Therefore, it is not advisable to judge whether blood pressure is elevated based on the presence or absence of symptoms alone, and it is necessary to measure blood pressure frequently. 5.For low back pain without a clear cause you should go to the hospital to check the kidneys, spine and low back muscles. 6.When a sudden decrease or steep increase in urine volume occurs without a fever, a lot of sweating, or a lot of drinking water, you should go to the hospital for the corresponding examination to confirm whether there is a kidney lesion. Frequent urination and low urine output often suggest the possibility of urinary tract infection. 7. If nocturia increases in young people, it may be an early clinical manifestation of kidney malfunction and should be especially noted. For the general population, routine comprehensive health checkups are the best way to detect kidney disease at an early stage, and regular urine routine and kidney function tests at the hospital can initially screen for chronic kidney disease. If urine protein and hematuria are detected in routine urine tests, it should be taken seriously and treated early so as to protect the kidneys. Moreover, since kidney function tests are more likely to be missed, it is worthwhile to ask the doctor to emphasize this item when issuing labs, as this test helps the kidney specialist to make a diagnosis of chronic kidney disease earlier.