”Dr. Liu, thank you so much! Look how much better the skin on his body is, he can feed himself and has gained weight.” A young couple holding a baby thanked Dr. Liu Dongmei, deputy chief physician, in the dermatology outpatient room of the Fifth Hospital in Jinhua City. Although the baby was only three months old, she was an “old patient” of the Fifth Hospital’s dermatology department, first seen at 21 days old. Dr. Liu Dongmei recalled that at that time, the child was brought in with hoarse crying, thin body, perioral, nostril, eye vulva, perianal erythema, pustules, yellow pustules, dry and flaky hands, erythema and pustules at the fingertips, partial nail involvement, perioral radiating lines, chapped and bleeding, blocked nostrils, purulent discharge from the corners of the eyes, red papules of varying sizes scattered on the body, perianal erosion and cracking, and constantly oozing out Liquid. Seeing such a situation, Dr. Liu Dongmei immediately considered that this is likely to be a congenital syphilis patient. The RPR result was 1:64 and TPHA(+). Dr. Liu clearly told the couple that the child had syphilis and that there was only one possibility that the mother was definitely infected with syphilis. At this point, the couple told Dr. Liu that they were both syphilis patients, and that they had married and had children because they never knew that syphilis could be transmitted to the next generation. Seeing the child’s miserable condition, the mother cried out and begged Dr. Liu to save the poor child. While comforting the couple, Dr. Liu Dongmei prescribed anti-syphilis medication for the child and instructed the parents to also undergo anti-syphilis treatment at the same time and make sure to adhere to a sufficient course of treatment. The RPR results also dropped to 1:16. Dr. Liu Dongmei told the couple that the child’s current condition is basically stable, but treatment will continue until the RPR turns negative. After the RPR has turned negative, they need to be followed up regularly. In addition, because the child is too young, it is necessary to continue to observe whether dental damage, hearing impairment and other symptoms will occur in the future. Although the child’s condition has basically stabilized after Dr. Liu Dongmei’s careful treatment, Dr. Liu’s heart has been very heavy. She hopes to use the media to appeal to which ignorant people, do not let the child carry the torment of the disease and pay for your absurdity, because the child is, after all, innocent. A. Syphilis is a sexually transmitted disease Dr. Liu Dongmei said that syphilis is a classic STD, a chronic systemic infection caused by the pale spirochete, or syphilis spirochete, a sexually transmitted disease Syphilis can cause damage and lesions in all tissues and organs of the body, producing malfunction, tissue destruction and even death. In recent years, with the opening of people’s sexuality, the incidence of syphilis in China has a tendency to increase. According to the different ways of infection, syphilis can be divided into acquired syphilis and congenital syphilis, according to the stage of disease can be divided into early syphilis (including stage I syphilis and stage II syphilis) and late syphilis, according to the clinical manifestations can be divided into manifest syphilis and latent syphilis. Congenital syphilis can be divided into early congenital syphilis (onset within 2 years of age) and late congenital syphilis (onset after 2 years of age). The incubation period of syphilis is 2-4 weeks, with an average of 3 weeks. Dr. Liu Dongmei said that the principle of syphilis treatment is: early diagnosis, early treatment, the earlier the treatment, the better the prognosis. Generally speaking, the cure rate of Phase I syphilis is more than 97%, the cure rate of Phase II syphilis is 90%, and late syphilis has produced organic lesions are not easy to recover. After treatment, it is important to make adequate follow-up, including clinical manifestations and serological examination, serological examination every 3 months in the first year, every 6 months in the second year, and once at the end of the third year. The patient’s sexual partner should be examined and treated at the same time. Here, Dr. Liu also wants to remind those patients that they must receive regular treatment at a regular hospital after getting sick, and should not be afraid to go to those private clinics or underground clinics for fear of embarrassment, resulting in loss of money and delayed illness. Second, syphilis can be prevented Dr. Liu Dongmei said, syphilis can be prevented, from the following three aspects, can effectively control the spread of syphilis. 1, control the source of infection. Syphilis patients are the main source of infection, early detection and early treatment is the best way to eliminate the source of infection. Therefore should be in premarital, preconception, prenatal, blood supply, employment, military, school, hospitalization and other medical examinations to make a good syphilis serum screening test. At the same time, special attention should be paid to some special high-risk groups such as prostitutes, prostitutes, drug addicts, regular syphilis serum screening test for them, so as to detect patients early and give immediate treatment. In addition, the syphilis patients have been found, are to mobilize their sexual partners to do the examination, confirmed infection should be treated in a timely manner. 2.Cut off the route of infection. Through publicity and education, make people aware of the harm of syphilis, consciously enhance their own awareness of prevention, do a good job of cleanliness, compliance with the law, do not engage in sexual promiscuity, to reduce the spread of syphilis. 3, reduce the harm to the next generation. Mothers with syphilis can transmit it to the next generation through the placenta, which is vertical transmission. Dr. Liu Dongmei said that it is the responsibility of the whole society to protect the next generation from syphilis. Therefore, it is very important to do the following. (1) Routinely do the serum screening test for syphilis before marriage, before pregnancy, 1-3 months after pregnancy, and 1-3 months before delivery to detect the disease early; (2) After regular treatment, syphilis patients can get pregnant as long as the clinical symptoms disappear and RPR returns to normal, without the need to have a psychological burden. However, if RPR is found to be positive during pregnancy, you should receive treatment immediately to effectively avoid the emergence of neonatal syphilis. (3) As long as one of the parents has syphilis, after the child is born, the child should be given a syphilis serum screening test early, early detection and early treatment. (4) Patients with fixed syphilis serotype, that is, syphilis patients after regular treatment with penicillin, doxycycline or roxithromycin and other drugs and adequate follow-up, RPR test for a long time to maintain a low titer such as 1:2 or 1:4. this situation is also possible to get pregnant, but during pregnancy must be required to receive syphilis serum screening test. After the birth of the child, the child must also be given a syphilis serum screening test for early detection of abnormalities.