For chronic hepatitis patients after a certain period of development, the disease will eventually go through the stage of liver fibrosis and ultimately develop into cirrhosis, and once in the stage of cirrhosis, the patient can be complicated by a variety of life-threatening complications, so how to block or delay the development of liver fibrosis to cirrhosis, and effective prevention and treatment of cirrhosis complications is to prolong the life of patients with chronic liver disease and improve the quality of life of the key. However, there are still some misunderstandings about the understanding of cirrhosis and even the treatment of cirrhosis. 1.Advanced cirrhosis is equal to the advanced stage of the disease and cannot be treated. Advanced cirrhosis is not equal to the advanced stage of the disease, through effective anti-virus, liver protection, correcting hypoproteinemia, preventing abdominal infection and other effective measures can well prolong the patient’s life and improve the quality of life. 2.Normal liver function does not need antiviral treatment. A few patients believe that they don’t need treatment after keeping liver function normal by taking all kinds of hepatoprotective drugs, but in fact, there are quite a number of patients with normal liver function for a long time, but liver cancer is found after some time, this is due to the fact that most of the patients with liver cancer in China are infected with hepatitis B virus, and the liver cells are cancerous under the long-term stimulation of HBV, therefore, patients with cirrhosis need antiviral treatment no matter whether their liver function is normal or not as long as they are positive for HBV-DNA. DNA is positive or not, as long as HBV- is positive, antiviral treatment is needed, and it needs to be used for life to prolong life as well as improve the quality of life. The treatment of ascites in decompensated stage of liver cirrhosis The formation of ascites in decompensated stage of liver cirrhosis is related to portal hypertension and hypoproteinemia, so it can be corrected by sodium restriction, application of large amount of diuretics, supplementation of albumin, etc. However, in daily work, we can see that some patients’ ascites subside faster through application of large amount of diuretics, but they feel weak and dry skin, etc. After checking electrolytes, they find that there are serious low sodium, low potassium, etc., and they can stop the treatment and have the treatment of ascites. After checking electrolytes, it is found that there is severe low sodium and low potassium, etc. After stopping diuretics, ascites is formed again very quickly, resulting in a vicious circle. Cirrhosis ascites need to be corrected patients with hypoproteinemia, reduce portal hypertension, etc. The rational use of diuretics can achieve twice the result with half the effort. Then through the above treatment there are still a part of the patient’s ascites subside unsatisfactory, a large amount of ascites easy to cause abdominal infection, serious can lead to the patient’s death. According to the definition of the International Ascites Association, refractory ascites is the early recurrence of ascites that cannot be prevented by medication after unsatisfactory regression of ascites after drug treatment or by discharge of ascites and other treatments with medication, and there are two subtypes: diuretics-resistant ascites and diuretics-refractory ascites. They can be treated by large amount of abdominal fluid discharge and expansion of blood volume, and by their own ascites concentration transfusion. Our department carries out ascites concentration and re-infusion for the treatment of refractory ascites, the basic principle of which is to utilize the limited permeability of the semi-permeable membrane to allow water and small molecules to pass through, retaining components such as albumin, which usually concentrates the ascites by 2 to 6 times, with sodium being removed in large quantities, and concentrated ascites by re-infusion can increase the effective blood volume and the sensitivity to diuretics, improve the renal function, inhibit the secretion of aldosterone and antidiuretic hormone, and reduce the application of exogenous albumin.