The main treatment for acute gout attacks is to relieve joint swelling and pain with medication. Three types of drugs are commonly used: non-steroidal anti-inflammatory analgesics, colchicine, and glucocorticoids. During the acute attack of gout, it is currently recommended that NSAIDs should be administered as early as possible (usually within 24 hours), such as etoricoxib, diclofenac sodium, celecoxib, loxoprofen sodium, etc. However, attention should be paid to the cardiovascular and gastrointestinal adverse effects of the drugs. Colchicine is also very commonly used during acute attacks of gout, but because of its high incidence of gastrointestinal adverse reactions and the fact that it is easily discontinued because of intolerance, colchicine is currently used only for patients in the acute phase of gout who have contraindications to the use of non-steroidal anti-inflammatory analgesics. If the patient’s condition is severe, the effect of conventional drug treatment is not good, or there are contraindications to the use of non-steroidal anti-inflammatory analgesics and colchicine, short-term use of glucocorticoids can be considered to control symptoms, using small and medium doses, oral, intramuscular or intravenous injection can be used, but the symptoms are easy to “rebound” after stopping the drug. Some patients with advanced disease and stubbornly difficult to control can be treated with biological agents such as anti-interleukin-1 and anti-tumor necrosis factor. In addition, it is recommended that patients can use ice packs during acute attacks to reduce joint pain and swelling. Therefore, gout attacks are mainly treated with drugs to relieve pain and control attacks. Patients should consult a doctor promptly and add medication as early as possible and in sufficient quantity under the guidance of a doctor to provide rapid relief of attacks and to develop a long-term control treatment plan.