Portal hypertension in cirrhosis is the number one cause of secondary hypersplenism in China, and when conventional medical treatment fails to correct portal hypertension itself and the secondary hypersplenism it causes, it is often necessary to turn to surgical treatment. Splenectomy is one of the commonly used methods; however, such patients often have abnormal hematological profiles and hepatic and renal insufficiencies that make the operation more dangerous. Also, because of the possibility of complicating a total splenectomy with an aggressive infection and the immunocompromised nature of patients with hepatic sclerosis, the risk of infection is bound to increase. 1. Relief of portal hypertension. As a result of partial embolization of the splenic artery, the blood returning to the portal vein through the splenic vein is reduced accordingly, thus indirectly relieving portal pressure and correcting a series of complications caused by portal hypertension such as intractable ascites. 2.Correct hypersplenism. 3.Prevent upper gastrointestinal hemorrhage caused by esophageal and fundic varices. 4.Preservation of spleen function. The main advantages of interventional treatment compared with traditional splenectomy in surgery are: the method is less traumatic to the patient and reduces the risk of bleeding and infection; its indications are also slightly wider than those of surgery, and interventional treatment can be performed on some patients who cannot tolerate surgery or do not want to operate. PSE implementation method: oral antibiotics are started 2-3 d before surgery to cleanse the intestine. Most PSEs are performed under local anesthesia and may be performed under general anesthesia in children. PSE can be divided into super-selective and non-super-selective, the former means to deliver the catheter into the terminal branch of splenic artery and make it completely embolized, mostly using ultra-micro catheter or balloon catheter to enter the middle and lower pole of splenic artery for precise embolization and The latter is a simple procedure in which the catheter is placed in the main trunk of the splenic artery and the embolic agent enters the various parts of the spleen at will with the blood flow, and is mostly used in addition to TACE to reduce hypersplenism. For giant spleen and hepatocellular carcinoma, fractionated PSE is advocated, especially for the latter, which requires repeated TACE and is safer to use fractionated PSE. An appropriate amount of antibiotics (e.g., gentamicin) should be mixed with the embolic agent to prevent infection. Postoperative broad-spectrum antibiotics are administered for 1 week to prevent splenic abscess, and liver-protective drugs and hormones are used to reduce the post-embolization syndrome response. Platelet and leukocyte counts rose to the highest level within 1 to 2 weeks after embolization, then fluctuated slightly and decreased slightly, and basically stabilized at a level higher than the preoperative level around 2 months. The rate of platelet and leukocyte elevation in the first 2 weeks was not related to the volume of the embolized spleen. After 2 months, the rate of leukocyte elevation was positively correlated with the volume of splenic infarction. Most of the postoperative pain and fever resolved within 1 week after symptomatic treatment, and none of the patients developed left pleural effusion or splenic abscess healed after treatment using superselection to the splenic inferior pole artery for embolization. The preventive approach is to strictly grasp the indications, make good preoperative preparation, and apply antibiotics postoperatively. Partial embolization of the splenic artery is a minimally invasive procedure that preserves the immune function of the spleen while effectively relieving hypersplenism and portal hypertension, and is an effective treatment route for patients with hypersplenism in liver cirrhosis.