Diabetic nephropathy: is a particularly common and troublesome complication of diabetes.DKD is generally divided into five stages. The clinical features are proteinuria, progressive renal impairment, hypertension, edema, and severe renal failure in the late stage, which is one of the most serious complications of diabetes and one of the main causes of death in diabetes. Second, the antecedents and consequences of diabetic nephropathy: 1, type 2 diabetes → diabetic nephropathy → renal failure → uremia (need dialysis). Prevention of diabetic nephropathy: 1. All diabetic patients are recommended to regularly check kidney function, urine protein characterization, 24-hour urine protein quantification and attention to the measurement of blood pressure to do fundus examination. Urine microprotein measurement and β2-microglobulin for early detection of DKD. 2, control of blood sugar, blood pressure. 3, emphasize low salt and low protein diet with high quality protein is better, both to ensure adequate calories and nutrition, but also to limit carbohydrates, fats and proteins, so, if available, should be under the guidance of dietitians or physicians, according to the condition, adjust the three meals a day. Fourth, the treatment of diabetic nephropathy: the recommended “combination of Chinese and Western medicine” approach. In other words, the high-tech technology and equipment of Western medicine are used to conduct laboratory tests and diagnose and stage the disease, and then the Chinese medicine treatment methods (looking, smelling, asking and cutting) are used to identify the patient and guide the next step of treatment. The main treatments are Chinese medicine for kidney protection, sugar reduction, blood pressure reduction, eye protection, peritoneal and hemodialysis.