Osteoporosis is a systemic bone disease characterized by reduced bone mass, destruction of bone microstructure, increased bone fragility and susceptibility to fracture, and is a common disease in the elderly. It is the most serious consequence of osteoporosis. The most common fracture sites are the spine, hip, distal radius and proximal humerus. Osteoporotic fractures are more common in women and more frequent in people over 60 years of age. They are most often the result of minor trauma (defined as an injury caused by a fall on level ground or at a high body weight) or without a history of significant trauma, and can occur even during daily activities. The Department of Spine and Orthopedics has established a systematic diagnosis and treatment program for osteoporosis, carrying out scientific and personalized treatment for different conditions, increasing patients’ bone mass and reducing the occurrence of serious complications such as fractures. Balloon expansion vertebroplasty is carried out to treat vertebral compression fractures caused by osteoporosis, relieving pain, repositioning and stabilizing the spine, restoring vertebral height, correcting spinal deformities, allowing early bedtime activities and returning to daily life.