Many people with gallbladder stones do not have any clinical symptoms, do they need surgery to remove their gallbladder? This is a concern for many patients, who are both fearful of surgery and worried about the day when complications arise. According to the Chinese Medical Association Biliary Group, a patient with gallbladder stones who meets one of the following conditions has an indication for surgery 1. Patients over 50 years old or found to have gallbladder stones for more than 5 years. Associated with prolonged stone irritation of the gallbladder mucosa that can be secondary to gallbladder carcinogenesis. 2. Patients with stones larger than 2 cm. The chance of cancer increases 0. 3. Patients with combined diabetes mellitus. Once the acute attack of cholecystitis, the chance of successful conservative treatment for diabetic patients is very small, and the disease progresses rapidly, and the proportion of gallbladder gangrene and perforation is much higher than that of ordinary people. 3. Porcelain gallbladder. Closely related to gallbladder cancer. 4. Filled gallbladder stones, in which the gallbladder is no longer functional. 5. Atrophic gallbladder. Atrophic gallbladder not only has no function, but also is prone to secondary gallbladder cancer. Therefore, patients with asymptomatic gallbladder stones that meet one of the above conditions should still accept the surgeon’s recommendation to undergo surgery, because after all, in these cases, the risk of complications is much greater than the risk of surgery, and the risk of laparoscopic gallbladder removal surgery is very small at present.