Simple difference between coma state and vegetative state It is often found in clinical work that most families, even including some doctors, cannot distinguish coma from vegetative state, and often treat vegetative state as coma, and call vegetative state as open-eyed coma, and the core is still coma. In fact, there is a big difference between coma and vegetative state. The vital signs (respiration, blood pressure, pulse, temperature) of comatose patients are generally unstable; the vital signs of patients in the vegetative state are generally relatively stable; that is, comatose patients are relatively critical, and patients in the vegetative state are relatively stable and safe. Patients in coma generally have closed eyes, while patients in vegetative state have open eyes, which is why some people call the vegetative state an open-eyed coma. Coma patients are generally in a continuous closed-eye state, that is, the majority of the day is closed, only occasionally open eyes, but soon closed; vegetative state patients open their eyes during the day and sleep at night, similar to normal people. Comatose patients do not have a sleep-wake cycle, while vegetative patients have a sleep-wake cycle. Comatose patients open their eyes normally and then generally show two results, one is fully awake, speech, movement and emotion (crying, laughing, happy, sad, angry, etc.) are not much different from normal people, which is what we see most and what we hope for; the second is that although the eyes are open, they do not respond to external stimuli, there is no speech, movement or emotion, and in general, they can be considered to have entered a vegetative state. Of course, a definitive diagnosis still needs to be determined by the clinician according to the diagnostic criteria.