There are many reasons for purple hands, including physiological factors as well as pathological factors, mainly related to the following conditions: a. Physiological factors when the weather is cold, the hands are exposed to cold resulting in poor blood circulation, blood stagnation in the capillaries, thus the phenomenon of purple hands. This situation belongs to the physiological factors, away from the cold environment, pay attention to keep warm can be alleviated. Second, the pathological factors of purple hands is a local skin and soft tissue hypoxia, ischemia, any disease that causes microvascular constriction of the hands may lead to purple hands phenomenon, common diseases are the following: 1, liver disease: liver disease patients due to hormone secretion disorders, resulting in subcutaneous vascular enlargement and expansion, easy to appear purple palms, red symptoms; 2, congenital heart disease: this type of patients if the blood left to right If these patients have left-to-right blood shunts and venous blood flows directly into the arteries, the phenomenon of purple extremities will appear; 3, blood circulation disorders: such as heart failure leading to low heart pumping function, the end of the extremities appear bruising changes; 4, anemia: patients may appear purple hands due to low hematopoietic function and local hypoxia; 5, Raynaud’s syndrome: patients have peripheral vasospasm during the onset, and then the phenomenon of purple fingertips; 6, chronic obstructive Pulmonary disease: some patients who have developed to the middle and late stages of respiratory failure for a long time, severe hypoxia, will lead to obvious purple symptoms on the extremities; 7, vascular diseases: arterial occlusive vasculitis is common, because of the lack of blood supply, resulting in local tissue hypoxia, thus appearing purple hands; 8, other: trauma, taking special drugs, etc. may appear purple hands.