Headache is one of the common clinical symptoms, and usually refers to pain confined to the upper part of the skull, including the brow arch, the supra-orbital rim and the area above the line of the external occipital ridge. The diagnosis of headache is often difficult because the patient cannot locate it accurately. Therefore, in addition to detailed medical history, detailed and comprehensive physical examination, relevant laboratory tests are also necessary, including blood pressure measurement, fundus examination, cranial CT scan, electroencephalogram, transcranial Doppler ultrasound and blood routine, blood glucose laboratory tests, and even cerebral angiography, etc. Of course, not all tests should be done, but some relevant tests should be done selectively according to the condition. And most headache patients, general painkillers are effective, but the maintenance time is short. 1.High cranial pressure headache: headache is located in the forehead and temporal top, with throbbing pain or swelling pain, obvious in the morning, stopping when it occurs, and even nausea and vomiting in heavy cases, and gradual loss of vision. At this time, we should be alert to intracranial tumor or hydrocephalus, and head CT and MRI examinations are needed to make a clear diagnosis. 2.Inflammatory irritation headache: If the headache is accompanied by fever, or a history of cold, the headache is tearing-like swelling pain, with violent vomiting, accompanied by chill, neck tonicity, pale face and increased blood picture. It can be seen in sinusitis, intracranial venous sinusitis, meningitis, etc. It is common in children and young adults. In middle-aged and elderly people, if they have never had a history of headache and suddenly develop severe headache or vague pain, they should be highly alert for ruptured intracranial aneurysm bleeding. Some patients do not pay attention to the first headache, and when the second bleeding occurs, the condition worsens, and most of them become coma and even lose the best time for treatment. Therefore, CT or MRI examination of the head should be performed promptly. In addition, glaucoma (combined with photophobia, tearing and blurred vision in both eyes) can also cause headache, and ophthalmologic examination is needed. 3. Neuropathic headache: If frontal facial pain without toothache and gingivitis, talking, eating and blowing wind can induce pain, it is mostly trigeminal neuralgia (carbamazepine is effective); if posterior occipital pinprick-like pain can be radiated upward, it is mostly occipital neuralgia; sometimes cervical spine osteophytes or cervical disc prolapse can also induce posterior occipital pain. Herpes simplex virus infection can be healed with a headache, which usually occurs instantly without signs and can be relieved after rest, and sometimes can be awakened by pain during sleep. In addition to painkillers, vitamin B drugs such as methylcobalamin should be taken. 4.Vascular headache: Before the headache attack, there may be signs of blackness and blurring in front of the eyes, which can be triggered by watching TV and computer screen. It may be more effective to take nimodipine, Cipro in combination with pain relievers (Disulfiram) or antidepressants (fluoxetine). 5.Anxiety-depression headache: prolonged poor rest, insomnia, emotional instability; headache is vague pain in the whole head with deeper parts, often with discomfort in other parts of the body. The symptoms vary in severity with mood fluctuations. The neurological examination is mostly abnormal, and there is no abnormality in CT or MRI of the head and EEG. This type of headache is more common in women than men, and 90% of them are related to mental tension, stress, anxiety and other psychological factors, especially in big cities with developed economy, which is called “urban disease”. The application of pain medication is often not ideal, but the use of antidepressants such as fluoxetine (Prozac), doxepin, amitriptyline and calcium channel antagonists (such as Cipro) is often effective. Since these patients are mostly young and middle-aged white-collar workers, antidepressants often cause patients to stop taking them at will for fear of being misunderstood as “neurotic”, resulting in recurrent headaches. Of course, with the increased mobility, employment pressure, family, marriage and interpersonal relationships or tension with supervisors and colleagues, it is difficult to adjust psychologically or to find a suitable solution and feel depressed, thus resulting in functional headache. Therefore, in the fast-paced, high-intensity, highly competitive modern lifestyle, each of us should face the stressful modern life with a healthy and optimistic attitude. Don’t just “go ahead, over-pursuing perfection and overspending the quality of your life”. Learn to give up, change the bad lifestyle, pay attention to the quality of life, actively engage in work and know how to enjoy life. The best way to live is to pay more attention to your health while achieving your career. Of course, the causes of headache are far from the above-mentioned causes, there are other causes and subtypes, so I won’t go into them all here.