In recent years, with the improvement of people’s living standards, we find that the incidence of gallbladder stones and cholecystitis is increasing year by year, and even more and more young people and children are suffering from them. Once gallbladder stones and cholecystitis develop into chronic cholecystitis, they face a new hidden danger DDD cancer, gallbladder can also become cancerous, this serious problem is often not known to many people, the process of gallbladder malignancy is very insidious, its cause of right upper abdominal vague pain patients often think it is caused by gallbladder stones or inflammation, ultrasound examination is also often only see stones without cancer, wait until the tumor grows up or even When the tumor grows and even “reveals its original shape”, most of them have lost the chance of radical treatment, and even if surgery is performed, the effect is not ideal. Of course, not all gallbladder stones and chronic cholecystitis are cancerous, but our research has found that there are some more special cases of chronic cholecystitis or gallbladder stones that are more likely to become cancerous. What kind of gallbladder has the possibility of cancer? 1.Older patients over 50 years old with recurrent attacks of chronic cholecystitis, especially women, have a dramatic increase in the cancer rate, accounting for about 80% of the total cases, with an average age of about 65 years old. However, the rate of gallbladder carcinoma does not increase in patients who have never had abdominal pain symptoms. 2. Chronic cholecystitis with longer disease duration (>5 years) and recurrent abdominal pain, especially atrophic cholecystitis (i.e. gallbladder size less than normal). There are stones in the gallbladder, especially those with multiple or full type stones. The cancer rate of calculous cholecystitis is 30 times higher than that of non-calculous cholecystitis, indicating the important role of stone irritation factors in cancer. Patients who have episodes of abdominal pain from time to time should especially pay attention to regular checkups. 3. Porcelain gallbladder. It is the end stage of chronic cholecystitis, and the cancer rate of porcelain gallbladder is as high as 20%. 4, combined with gallbladder polyps, gallbladder adenoma and adenomyosis. The cancer rate of polyp ≥10mm is as high as 23%. 5.B ultrasound indicates significant thickening or limited thickening of gallbladder wall. 6.The diameter of gallbladder stone is greater than 2.0 cm. As the volume of gallstones increases, the incidence of gallbladder cancer increases accordingly, and the incidence of gallbladder cancer is 10 times higher for stones larger than 2.0 cm in diameter than those smaller than 1 cm. 7. Those who have previously undergone cholecystostomy. Prevention of gallbladder cancer: 1. Those who have recurrent abdominal pain should be treated thoroughly with cholecystitis and cholelithiasis through surgery as soon as possible. 2. Pay attention to dietary habits, have regular meals and eat less greasy food, especially barbecued and fried food. In addition, increasing the intake of fresh vegetables and fruits can reduce the risk of gallbladder cancer. 3. The incidence of gallbladder cancer is also high among those who are severely overweight; obese people should actively lose weight and control their weight. In conclusion, we can prevent gallbladder cancer through a series of methods, the key is whether we pay attention to it or not.