(Disclaimer: This article is only for popular science purposes, in order to protect the privacy of patients, the following content of the relevant information has been processed) Abstract: The case of the patient 2 weeks ago appeared in the lower limbs of the pain, the symptoms are obvious during the activity, the symptoms are reduced at rest, due to the failure to pay attention to the treatment, leading to the existence of the pain aggravation and other serious impact on the quality of life of the patient, and then came to our hospital for medical treatment. After admission, the patient was finally diagnosed with bone tuberculosis through relevant examinations, and after a period of anti-tuberculosis treatment, the patient’s symptoms have basically improved. Basic information] Female, 65 years old [Type of disease] Bone tuberculosis (spinal tuberculosis) [Hospital] The First Affiliated Hospital of Zhengzhou University [Date of consultation] July 2021 [Treatment plan] Drug treatment (celecoxib capsules for pain relief, isoniazid tablets, rifampicin capsules, pyrazinamide tablets, ethambutol hydrochloride tablets) + Surgery (bone grafting with posterior lesion removal and internal fixation via the pedicles) [Period of treatment Hospitalization for 2 weeks, outpatient regular review for 1 year 【Treatment effect】Patient’s symptoms have basically improved I. Initial consultation After the patient came to the outpatient clinic, he complained of sudden swelling and pain in the left lower limb after getting cold 2 weeks ago, accompanied by obvious pain when walking, but the pain would be relieved when lying down and resting, and he did not have any abnormalities, such as fever and fear of cold, etc. At first the patient thought that low back and leg pains at his own age was normal, so he did not do any treatment. At first, the patient thought it was normal to have back and leg pain at his age and did not do any treatment. Recently, however, the pain was aggravated, accompanied by pain in the lower leg and the back of the foot, so he came to our hospital for consultation. After the patient was admitted to the hospital, the examination showed negative straight leg raising test bilaterally, no edema in both lower limbs, normal nerve reflexes, and lumbar spine CT suggested that part of the intervertebral disc was bulging. Chest CT suggested that the patient had old tuberculosis foci in the lungs, stool routine was normal, blood sedimentation was 15mm/h, and tuberculin test was positive. Combined with the patient’s symptoms, physical examination, and nuclear magnetic examination, the diagnosis of spinal tuberculosis was clear. The patient and his family explained his condition and treatment plan, and the patient and his family agreed to undergo drug+surgery treatment. As the patient’s pain was obvious, celecoxib capsules were given to relieve pain, and isoniazid tablets, rifampicin capsules, pyrazinamide tablets, and ethambutol hydrochloride tablets were given to treat the pain, and the side effects of the medicines were closely observed in the process of the treatment. 2 weeks later, the patient’s tuberculosis toxicity symptoms were reduced, and the patient was given a posterior pathway lesion removal bone grafting, and transpedicular endoprosthetic surgery. The patient recovered well after the operation, and there was no sign of infection, and the family took good care of the patient, and the patient did not develop decubitus ulcers. During hospitalization, the patient’s basic signs were stable, and after discharge, he continued to receive anti-tuberculosis treatment and came for regular checkups. Up to now, the patient has been on the medication for 1 year, and his condition has gradually stabilized, and his blood counts are within the normal range, and there are no obvious abnormalities in his blood sedimentation and liver function. Precautions Seeing the patient’s symptoms gradually reduced, I feel very pleased, but in order to the patient’s health, we also need to remind the patient’s daily life to pay attention to the following points: 1, the patient pays more attention to warmth in the fall and winter, in order to avoid cold, exertion aggravate the condition; 2, pay more attention to supplementing the nutrition in the diet, you can consume more easy to digest, as well as more protein-containing foods, such as milk, eggs, beef, etc., but avoid eating spicy stimulating food, such as Spicy stimulating food, such as chili, onion, garlic, etc.; 3, daily life, patients can increase the appropriate exercise to enhance their own immunity, but need to pay attention to gradual and orderly, while avoiding too intense exercise. V. Personal perception The patient’s illness is not only related to the poor immunity caused by his age, but also related to the usual cold and other factors. Usually, bone tuberculosis occurs in children, adolescents and the elderly, and is a destructive lesion caused by the invasion of tuberculosis bacteria into the patient’s skeletal system, and the treatment is mainly drug therapy. It should be noted that, because of the large side effects of anti-tuberculosis drugs, patients should be reminded to pay attention to regular review, after the emergence of anomalies, by informing the doctor and program adjustments, as long as the treatment is timely, the majority of patients with bone tuberculosis can get a more satisfactory prognosis.