Tuberculosis of the bone is a relatively serious disease which is a destructive disease produced by the invasion and destruction of bone or joint structures by the tuberculosis bacillus. It is generally assumed that tuberculosis bacilli tend to be found in lung tissue, but in fact they can be found in most organs of the body, and bone tuberculosis is a very serious form of tuberculosis in addition to lung tuberculosis. Bone tuberculosis develops mostly in the joints that are more weight-bearing, more active and prone to strain, such as the hip, knee and spine. Usually patients with bone tuberculosis will have different clinical manifestations depending on the location of the tuberculosis. For example, tuberculosis of the lumbar spine may produce a fluid-filled abscess, which produces pain in the lumbar region, limitation of movement, compression of the nerve roots, and symptoms such as numbness and weakness of both lower limbs. Patients with bone tuberculosis usually have a history of tuberculosis, especially pulmonary tuberculosis, or a history of exposure to tuberculosis. The disease usually starts slowly, and there may be pain in the affected joints, tenderness, and pain on percussion, and there may also be symptoms of tuberculosis toxicity, such as low-grade fever, night sweats, poor appetite, weight loss, and generalized fatigue and weakness. As the condition of bone tuberculosis progresses, joint deformity will also occur, and if the tuberculosis breaks down and forms a skin sinus tract, the condition is usually prolonged and difficult to be cured. In conclusion, bone tuberculosis is a kind of serious and tricky tuberculosis, which not only requires surgical treatment, but also is difficult to treat, and is easy to leave deformity and dysfunction and other consequences.