Ankylosing spondylitis is mainly pain in the lower back, back, buttocks, groin, lower extremity joints, thorax, and neck, and is not limited to 6 places. The pain and stiffness usually start first in the lower back and hips, and then the pain can slowly extend up and down and eventually invade the entire spine and even the joints of the lower extremities. Patients can observe typical bamboo-like changes in the spine on X-rays through imaging. The main manifestations of ankylosing spondylitis are lower back pain, discomfort, pain and stiffness in the joints at the base of the thighs. In the early stages, the stiffness of the affected area is usually more pronounced when the patient wakes up in the morning or when he or she is sedentary, and the discomfort can be relieved after activity. In the later stages, the symptoms expand upward to the thorax and neck, and downward to the large joints of the lower limbs, knees and ankles, resulting in stiffness and pain typical of ankylosing spondylitis in all of these areas. In the late stages of ankylosing spondylitis, the symptoms are not only joint pain and stiffness, but can also progress to spinal stiffness and deformity. Patients may show forward extension of the head and backward protrusion of the thoracic spine, eventually causing hunchback deformity and even complications such as osteoporosis, iritis, and interstitial pneumonia. The inability to rotate the neck and lumbar region and the need to rotate the whole body when viewing objects can also cause inconvenience in mobility. The main treatment goals for ankylosing spondylitis are to relieve pain, prevent the development of deformities, and improve quality of life. Those with severe pain can start with non-steroidal anti-inflammatory drugs such as acetaminophen, aspirin, and ibuprofen for analgesia and anti-inflammation. In addition, patients are encouraged to perform spinal exercises to maintain proper posture and prevent hunchback. For those with severe symptoms or those who have developed spinal deformity, surgical correction can also be performed.