Ankylosing spondylitis is a systemic disease of unknown origin, with chronic inflammation of the mid-axis joints as the main cause. It mainly involves the sacroiliac, hip, intervertebral, and cribriform joints, with sacroiliac joint lesions being the most common and occasionally causing small joint lesions in the extremities. The common symptoms are stiffness or pain in the lower back, which may be relieved by activity. In advanced stages, spinal ankylosis and deformity may occur to the point of severely impaired function. The clinical manifestations of ankylosing spondylitis belong to the category of “paralysis” or “lumbago” in Chinese medicine. The basic pathogenesis of this disease is congenital deficiency, weakness, deficiency of essence and blood in the liver and kidney, deficiency of the kidney governor, the evil of wind, cold and dampness invading the kidney governor, or the evil of cold and dampness turning into heat after a long period of time, resulting in the disorder of tendons and veins and damage to bone. The nature of this deficiency is the real, the deficiency of the liver and kidney is the root, and the wind, cold and damp heat are the symptoms. Identification and treatment: 1, liver and kidney deficiency, cold and damp paralysis: Symptoms: lumbosacral, spinal pain, pain even neck, back cold, limb soreness heavy, or morning lumbosacral, back stiffness pain, unfavorable activity, warmth pain reduction, thin white tongue coating, sunken string pulse. The treatment is to tonify the liver and kidney, dispel cold, remove dampness, and promote circulation. The formula is based on the following formula: Cornus officinalis 15g, Yam 15g, Radix Rehmanniae 15g, Gui 10g, Phellodendron 9g, Semen Cuscutae 15g, Deer horn gum 15g, Dulcimer 12g, Angelica Sinensis 15g, Qiangwu 10g, Douhu 10g, Hessian 3g. Add to 15g; if the lumbar pain is obvious, add Sang Sang Sang 30g; if the shoulder and back are stiff and painful, add Pueraria Mirifica 15g. 2, liver and kidney deficiency, damp-heat paralysis and obstruction: Symptoms: pain in the lumbar back, stiffness and discomfort in the morning, restricted movement, heat when the affected skin is touched, increased pain in the lumbar back at night, difficulty in turning over, or with low-grade fever, limbs like to be put outside at night, bitterness and thirst without desire to drink, constipation and urinary redness, red tongue, yellowish greasy coating, slippery pulse. The treatment is to tonify the kidney, benefit the governor, clear heat and dampness, and promote circulation. If the eyes are red and red, fearing light and shyness, add 15g of Xia Gu Cao, 12g of Celosia, 12g of Mucuna pruriens; if the chest is stuffy like a bundle, add 15g of Citrus aurantium. 3, liver and kidney deficiency, phlegm and stagnant paralysis: Symptoms: pain in the lumbosacral and backbone, ankylosing deformity of the neck and spine, unfavorable prostration and lateral rotation, restricted movement, chest tightness, accompanied by dizziness and tinnitus, low fever or cold extremities, dull complexion, purple lips and tongue, white and greasy coating, thin and astringent or slippery pulse. The treatment is to tonify the liver, benefit the kidney, remove phlegm and eliminate blood stasis, and promote circulation. The formula is based on Hu Qian Wan and Shuang He San: Tortoise Board 15 g, Shu Di 15 g, Cornu Cervi Pantotrichum 15 g, Dog Root 12 g, White Peony 15 g, Chen Pi 15 g, Radix Panax Notoginseng 12 g, Zhi Mu 15 g, Angelica Sinensis 12 g, Chuan Xiong 12 g, Cistanches 15 g, Qing Feng Vine 15 g, White Mustard Seed 9 g, Curcuma Longae 10 g, Tu Bei Mu 10 g, Pierced Mountain Dragon 15 g, Sang Sang Sang 15 g. Add and subtract: Artemisia annua 12g, Radix et Rhizoma Dioscoreae 30g, Radix gentianae 15g for low fever and five heartburn; add Xianmao 12g, Epimedium lappa 15g, Bacopa monniera 12g for obvious Yang deficiency.