Thigh pain, numbness may be caused by the following two reasons: First, the most common cause of thigh pain, numbness is lumbar disc herniation, when suffering from lumbar disc herniation, the protruding lumbar disc will compress the nerve roots, triggering the symptoms of sciatica. Once the sciatic nerve injury, irritation phenomenon will lead to thigh pain, numbness. Second, thigh pain, numbness may also be caused by the sciatic nerve lesion itself, including the sciatic nerve injury caused by the pear-shaped muscle syndrome, or various sharp and blunt injuries to the sciatic nerve, as well as the sciatic nerve injury caused by intramuscular injections, can lead to thigh pain, numbness.