Principles of treatment for early congenital syphilis —- The earlier the treatment, the better the effect —- The treatment must be regular, sufficient amount and full course —- Penicillin treatment is preferred —- Regular follow-up after treatment —- Treatment goal: disappearance of symptoms and seroconversion —- When the sick child has much and severe visceral damage, the treatment is first based on life saving, carefully and cautiously to avoid severe Hirschsprung’s reaction.