The full name of “mesoplasia” is central pulpy chorioretinopathy. It is one of the most common fundus diseases. Most of the patients are young and middle-aged men, and they often develop in one eye. What will patients feel if they have “central pulp”? The first is the loss of vision: the vision of the diseased eye suddenly decreases, and the visual acuity is usually not less than 0.5, and the worst is not less than 0.2. Secondly, the patient will have a central dark spot: the patient will complain of a disc-shaped shadow in the center of the visual field. Third, the diseased eye becomes smaller and straight lines become distorted compared to the healthy eye. If the above symptoms appear, patients are recommended to come to the hospital in time for consultation. The most important and quickest examination is optical coherence tomography (OCT), which can detect “layering” of the retinal macula and macular edema. In addition, patients should also undergo fundus fluorescence angiography to clarify the extent and severity of the lesion. Most of the cases can be cured by themselves. Patients can take oral medication such as vitamin C, E, B12, etc. under the guidance of doctors, and add drugs to reduce capillary permeability. It takes about six months for the deformation and darkening of the view to disappear gradually. However, in some cases, the disease is recurrent, resulting in irreversible damage to visual function, and these patients should undergo fundus laser treatment. Because the disease is mostly triggered by mental tension, overexertion, decreased body resistance, external cold and other factors, so we should pay attention to prevention and early treatment. It is important to arrange the work and rest schedule reasonably and combine work and rest to avoid the many factors that trigger this disease. In case of the disease, there is no need to worry about it, you should rest properly, avoid excessive brain and physical labor, and follow the medical advice on medication.