Mesoplasmosis, short for central plasmacytoid retinopathy, is a self-limiting disease confined to the posterior pole of the eye with a good prognosis. Mesoplasmosis is a disruption of the barrier function of the retinal pigment epithelium, causing plasmacytic detachment of the retinal sensory layer. It may be associated with emotional stress, mental stress, infection, injury, and other factors. It is more common in young and middle-aged males. There is significant visual distortion. There are no particularly effective drugs for treatment. The Amsler chart (see below) can be used to examine the central visual field up to 10 degrees and observe the visual distortion. The chart is viewed with one eye during the examination. Under normal conditions, you can see that the table has straight lines and each small cell is square. 1.People with visual distortion can find uneven lines or squares in the Amsler table. 2.People with microsightedness may find that some of the cells in the square table are particularly tight, as if some of the gauze in the dressing had been drawn tight. 3.Patients with macropia will find that some cells are irregularly enlarged. 4.Persons with relative central dark spots may find that some of the respective lines are blocked by a mist, and sometimes these lines or grids are not even clearly visible or disappear. Relative central dark spot may also have visual distortion.