There is no clinical best way to treat middle plasma disease, because the lesion site and disease progression of each patient, etc., are different. Therefore, the treatment methods adopted are also different. The main methods of treatment include: clinical observation, laser photocoagulation, photodynamic therapy and so on. 1. Clinical observation: Mesoplasmosis is a self-limiting disease and most patients can recover on their own without treatment. Therefore, continuous clinical observation is mostly considered for patients with mild disease. 2. Laser photocoagulation: After fundus angiography, the location of retinal leakage point can be clarified. If the leakage point is far away from the macular center, retinal photocoagulation can be considered to close the leakage point in time. 3. Photodynamic therapy: If the leakage point is close to the macular center, photodynamic therapy can be considered. In the clinic, there is no best treatment method for MTP, only the most suitable method. It is recommended that the patients should consult the doctor for examination in time, so as to carry out targeted treatment according to their conditions.